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Computational Biologist
Sanford-Burnham Medical Research Institute

We are seeking to recruit a skilled computational biologist with experience developing analysis and database integration solutions for orthogonal systems-level datasets, including high throughput genomics, proteomics, and microarray/NGS. Knowledge of bioinformatics is required, particularly hands on experience in the area of statistics, protein network analysis, pathway enrichment analysis, gene expression clustering are important. The candidate will develop novel methods, extend, adapt and improve existing methods.

Qualifications: This position requires the knowledge and skills normally acquired through completion of a PhD in bioinformatics, statistics, computer science, computational biology, or engineering (MS acceptable for the candidate with the right experience). Programming skills in R/Perl on a UNIX platform and knowledge of machine learning approaches is preferred. Rapid prototyping experience is essential.

Please visit http://www.chandalab.org for more information.

Post-Doctoral Fellow: Host-Pathogen Interactions and Innate Immunity
Sanford-Burnham Medical Research Institute

Immediate opening(s) in the laboratory of Dr. Sumit K. Chanda for scientists with a background in one or more of the following areas: Molecular Virology (RNA viruses) & Innate Immunology/Pattern Recognition Receptor Responses. Projects will involve employing systems-based technologies to establish a global understanding of host-pathogen interactions that regulate cellular responses to viral infection, and inhibit viral replication. Studies will integrate both large-scale technologies (RNAi, AP-MS, NGen seq, etc.), and more traditional cell & molecular biology and biochemistry-based approaches. A background in systems- or computational biology is not essential. Positions are supported by NIH funding.

We are seeking highly motivated and collaborative applicants with a MD, PhD, or equivalent doctoral degree, and 0-2 years of post-doctoral training. Prospective applicants should have a made significant contributions to their area of study as evidenced by a strong publication record in high impact journals.

Please visit http://www.chandalab.org for more information.

Interested, qualified applicants are encouraged to send their Curriculum Vitae, including names and correspondence of three references to Crystal Herndon at cherndon@sanfordburnham.org

Postdoctoral Fellow or Research Associate: HIV Regulatory Biology

A postdoctoral fellowship is available in the lab of Dr. Leor Weinberger (UCSD, Dept. of Chemistry & Biochemistry). Applicants with backgrounds in HIV molecular biology, HIV transcriptional regulation, or mathematical modeling of HIV are highly encouraged to apply.

The specific research project is flexible and can be tailored to the interests of the individual, but the research will focus on analysis of HIV gene expression and the temporal regulation of HIV gene-expression dynamics.

Applicants will be considered from a diverse spectrum of backgrounds but preference will be for highly motivated applicants with excellent communication skills and a proven record of independent research. The postdoctoral fellowship provides a competitive annual stipend plus benefits and health insurance. Start date and term are negotiable. The position is for one year to start, but funding for subsequent years is available pending satisfactory performance.

The Weinberger lab at UCSD is a joint experimental and modeling lab that studies HIV-1 and herpesvirus gene-circuit dynamics at the single-cell level using a combination of experimental and theoretical approaches (http://weinbergerlab.ucsd.edu). Applications are welcome from candidates of any nationality and will be reviewed on a rolling basis. UCSD offers an outstanding intellectual environment (each with many top-five ranked scientific departments, including Biochemistry and Bioengineering), and highly regarded medical schools. UCSD also houses a Center for Theoretical Biological Physics (CTBP), the newly formed San Diego Center for Systems Biology (SDCSB), the Biocircuits Institute (BCI), a world-class Center for AIDS Research (CFAR), and close proximity to the Salk and Scripps Institutes. Highly motivated applicants are encouraged to email a statement of research interests, CV, and contact details for three references to lsw (at) ucsd.edu. Informal inquiries are also welcome. The University of California is an affirmative action/equal opportunity employer. Review of application will begin immediately and will continue until the position is filled.

Postdoctoral Fellow: Innate Immune Signaling

If you have a background in signaling biochemistry and/or single cell imaging studies, and would like to work within an interdisciplinary team of experimentalists and computational modelers within the Signaling Systems laboratory, within the HIV Immune Network Team (HINT) and the San Diego Systems Biology (SDCSB), send coverletter and CV to: ahoffmann [at] ucsd.edu